At the close in New York, the Dow Jones shed 0.45%, the S&P 500 shed 0.14% and the NASDAQ Composite shed 0.05%.

In the leaders of growth among the components of the Dow Jones at the end of today's trading were shares of Intel Corporation, which rose in price by 1.77 points (3.31%), to close at 55.21. Merck & Company Inc added 2.58% or 2.07 points to end trade at 82.37. UnitedHealth Group Incorporated rose 1.40% or 6.40 points to end at 465.00.

The biggest losers were Nike Inc, which fell 4.16% or 6.53 points to end the session at 150.44. Boeing Co shares were up 2.87% or 6.19 points to end at 209.31, while Visa Inc Class A was down 2.30% or 4.99 points to 211. , 97.

The leaders of growth among the components of the S&P 500 index at the end of today's trading were shares of Moderna Inc, which rose in price by 9.28% to the level of 233.70, Humana Inc, which gained 6.06%, to close at 385.18, as well as shares Hologic Inc, which were up 4.47% to end at 73.45.

The biggest losers were Take-Two Interactive Software Inc, which fell 13.13% to close at 142.99. Cardinal Health Inc shed 5.92% to end the session at 51.03. Estee Lauder Companies Inc was down 5.36% to 335.89.

The top gainers among the components of the NASDAQ Composite index at the end of today's trading were shares of Bone Biologics Corp, which rose 57.14% to reach 5.39, Zynga Inc, which gained 40.67% to close at 8.44, and Molecular Partners AG ADR shares rose 30.22% to end at 21.50.

The biggest losers were TDH Holdings Inc, which fell 81.86% to close at 0.740. Kidpik Corp shares lost 27.47% and ended the session at 4.75. Rapid Micro Biosystems Inc was down 21.23% to 7.20.

On the New York Stock Exchange, the number of securities that fell in price (2052) exceeded the number of those that closed in positive territory (1186), while the quotes of 158 shares remained practically unchanged. On the NASDAQ stock exchange 2,493 companies fell in price, 1,368 increased, and 206 remained at the level of the previous close.

Take-Two Interactive Software Inc fell to a 52-week low, down 13.13%, 21.61 points to trade at 142.99. TDH Holdings Inc fell to a 52-week low, down 81.86%, 3.340 points to trade at 0.740. Kidpik Corp's shares fell to historic lows, down 27.47%, 1.80 points, to close at 4.75. Molecular Partners AG ADR rose to all-time highs, up 30.22%, 4.99 points, to close at 21.50. Rapid Micro Biosystems Inc fell to historic lows, down 21.23%, 1.94 points to end at 7.20.

The CBOE Volatility Index, which measures the value of S&P 500 options trading, was up 3.41% to trade at 19.40.

Gold Futures for February delivery was up 0.21% or 3.85 to $ 1.801.25 a troy ounce. Elsewhere in commodities, WTI crude for February delivery fell 0.62%, or 0.49, to $ 78.41 a barrel. Futures contracts for Brent oil for delivery in March were unchanged 0.00%, or 0.00, to trade at $ 81.02 a barrel.

Meanwhile, on the Forex market, EUR / USD was up 0.03% to hit 1.1327, while USD / JPY was flat 0.00% to hit 115.20.

The US Dollar Index Futures was up 0.23% at 95.938.